Bioconductor’s multtest package

1 Overview The multtest package contains a collection of functions for multiple hypothesis testing. These functions can be used to identify differentially expressed genes in microarray experiments, i.e., genes whose expression levels are associated with a response or covariate of interest. Introduction to multiple testing. This document provides a tutorial for using the multtest package. For a detailed introduction to multiple testing consult the document multtest.intro in the inst/doc directory of the package. See also Shaffer (1995) and Dudoit et al. (2002) for a review of multiple testing procedures and complete references. Multiple testing procedures implemented in multtest. The multtest package implements multiple testing procedures for controlling different Type I error rates. It includes procedures for controlling the family–wise Type I error rate (FWER): Bonferroni, Hochberg (1988), Holm (1979),